Diltiazem is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

Diltiazem is used to treat hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders.

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  • Cardizem, Cartia XT, Dilacor XR, Dilt-CD, Diltia XT, Diltzac, Matzim LA, Taztia XT, Tiazac
  • More common
    Body aches or pain
    congestion
    cough
    dryness or soreness of the throat
    fever
    hoarseness
    runny nose
    tender or swollen glands in the neck
    trouble swallowing
    voice changes
    Less common
    Chest pain or discomfort
    chills
    diarrhea
    difficult or labored breathing
    feeling faint, dizzy, or lightheaded
    feeling of warmth or heat
    flushing or redness of the skin, especially on the face and neck
    general feeling of discomfort or illness
    headache
    joint pain
    loss of appetite
    muscle aches and pains
    nausea
    shivering
    slow or irregular heartbeat
    sweating
    swelling of the hands, ankles, feet, or lower legs
    tightness in the chest
    trouble sleeping
    unusual tiredness or weakness
    vomiting
    Incidence not known
    Blistering, peeling, or loosening of the skin
    itching
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    no heartbeat
    red skin lesions, often with a purple center
    red, irritated eyes
    sores, ulcers, or white spots in the mouth or on the lips
    Severity: Minor
    Some of the side effects that can occur with diltiazem may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Sneezing
    stuffy nose
    Less common
    Acid or sour stomach
    belching
    constipation
    continuing ringing or buzzing or other unexplained noise in the ears
    degenerative disease of the joint
    difficulty with moving
    hearing loss
    heartburn
    indigestion
    lack or loss of strength
    muscle aching or cramping
    muscle pains or stiffness
    pain or tenderness around the eyes and cheekbones
    rash
    stomach discomfort, upset, or pain
    swollen joints
    Incidence not known
    Hair loss or thinning of the hair
  • (oral tablet, intravenous solution, oral tablet, extended release, intravenous powder for injection, oral capsule, extended release, compounding powder)