Treating tonic-clonic (grand mal) and partial seizures. It is also used to prevent and treat seizures that may occur during or after brain or nervous system surgery. It may also be used for other conditions as determined by your doctor.

Dilantin Kapseals extended-release capsules are an anticonvulsant. It works in the brain to block the spread of seizure activity.

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  • Examples include Dilantin Kapseals and Phenytek
  • All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

    Constipation; dizziness; drowsiness; headache; mild nervousness; nausea; trouble sleeping; vomiting.

    Seek medical attention right away if any of these SEVERE side effects occur:
    Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, eyes, face, lips, or tongue); bone pain; burning, numbness, or tingling; butterfly-shaped rash on the face; chest pain; clumsiness or unsteadiness; confusion; delirium; new or worsening mental or mood changes (eg, agitation, anxiety, behavior changes, depression, irritability, panic attacks, restlessness, suicidal thoughts or attempts); new or worsening seizures; red, swollen, blistered, or peeling skin; severe muscle pain; severe or persistent trouble sleeping; signs of infection (eg, chills, fever, sore throat); slurred speech; sores in the mouth or around the eyes; swollen lymph nodes; swollen or tender gums; symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, stomach pain, yellowing of the skin or eyes); tremor; trouble walking; unusual bruising or bleeding; unusual eye movements; unusual muscle movements; unusual tiredness or weakness.
  • Divided daily dosage Patients who have received no previous treatment may be started on one 100-mg Dilantin (extended phenytoin sodium capsule, USP) three times daily and the dosage then adjusted to suit individual requirements. For most adults, the satisfactory maintenance dosage will be one capsule three to four times a day. An increase up to two capsules three times a day may be made, if necessary. Once-a-day dosage In adults, if seizure control is established with divided doses of three 100-mg Dilantin (extended phenytoin sodium capsules, USP) daily, once-a-day dosage with 300 mg of Dilantin (extended phenytoin sodium capsules, USP) may be considered. Studies comparing divided doses of 300 mg with a single daily dose of this quantity indicated absorption, peak plasma levels, biologic half-life, difference between peak and minimum values, and urinary recovery were equivalent. Once-a-day dosage offers a convenience to the individual patient or to nursing personnel for institutionalized patients and is intended to be used only for patients requiring this amount of drug daily. A major problem in motivating noncompliant patients may also be lessened when the patient can take this drug once a day. However, patients should be cautioned not to miss a dose, inadvertently. Only Dilantin (extended phenytoin sodium capsules, USP) are recommended for once-a-day dosing. Inherent differences in dissolution characteristics and resultant absorption rates of phenytoin due to different manufacturing procedures and/or dosage forms preclude such recommendation for other phenytoin products. When a change in the dosage form or brand is prescribed, careful monitoring of phenytoin serum levels should be carried out.