Digoxin springs from the leaves of a digitalis plant. Digitalis helps create the guts beat stronger and with a a lot ofregular rhythm.

Digoxin is employed to treat coronary failure.

Digoxin is additionally wont to treat cardiac arrhythmia, a cardiac rhythm disorder of the atria (the higher chambers of the guts that permit blood to flow into the heart).

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  • Lanoxin, Lanoxicaps, Cardoxin, Digitek
  • Get emergency medical help if you have signs of an allergic reaction to digoxin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Call your doctor at once if you have:

    nausea, vomiting, loss of appetite;
    fast, slow, or uneven heart rate;
    bloody or black, tarry stools;
    blurred vision, yellowed vision; or
    confusion, hallucinations, unusual thoughts or behavior.
    Serious side effects may be more likely in older adults and those who are ill or debilitated.

    Common digoxin side effects may include:

    nausea, diarrhea;
    feeling weak or dizzy;
    headache, weakness, anxiety, depression;
    enlarged breasts in men; or
    mild skin rash.
  • Usual Adult Dose of Digoxin for Congestive Heart Failure: Rapid Digitalization with a Loading Dose: Peak digoxin body stores of 8 to 12 mcg/kg generally provide a therapeutic effect with minimum risk of toxicity in most patients with heart failure and normal sinus rhythm. The loading dose should be administered in several fractions, with approximately half the total given as the first dose. Additional fractions of the total dose may be given at 6 to 8 hour intervals. Careful assessment of the patient's clinical response should be considered before each additional dose. If the patient's response necessitates a change from the calculated loading dose of digoxin, then calculation of the maintenance dose should be based upon the amount actually given. Tablets: Initial: 500 to 750 mcg usually produces a detectable effect in 0.5 to 2 hours with a maximal effect in 2 to 6 hours. Additional doses of 125 to 375 mcg may be given at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin tablets that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 750 to 1250 mcg. Capsules: Initial: 400 to 600 mcg of digoxin capsules generally produces a detectable effect in 0.5 to 2 hours with a maximal effect in 2 to 6 hours. Additional doses of 100 to 300 mcg may be given cautiously at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin capsules that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg. Injection: Initial: 400 to 600 mcg of digoxin intravenously usually produces a detectable effect in 5 to 30 minutes with a maximal effect in 1 to 4 hours. Additional doses of 100 to 300 mcg may be given cautiously at 6 to 8 hour intervals until clinical evidence of an adequate effect is noted. The usual amount of digoxin injection that a 70 kg patient requires to achieve 8 to 12 mcg/kg peak body stores is 600 to 1000 mcg. The injectable route is frequently used to achieve rapid digitalization, with conversion to digoxin tablets or digoxin capsules for maintenance therapy. Maintenance Dose: The doses of digoxin tablets used in controlled trials in patients with heart failure have ranged from 125 to 500 mcg once daily. In these studies, the digoxin dose has been generally titrated according to the patient's age, lean body weight, and renal function. Therapy is generally initiated at a dose of 250 mcg once daily in patients under age 70 with good renal function.