Acetazolamide reduces the activity of a protein in your body called carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body.

Acetazolamide is used in people with certain types of glaucoma to reduce the amount of fluid in the eye, which decreases pressure inside the eye.

Acetazolamide is also used as a diuretic (“water pill”) in people with congestive heart failure, to reduce the build-up of fluid in the body. This build-up is called edema.

Acetazolamide is also used to treat certain types of seizures, and to treat or prevent altitude sickness

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  • Diamox, Diamox Sequels
  • Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    Call your doctor at once if you have:

    blood in urine or stools;
    a seizure (convulsions);
    loss of movement in any part of your body;
    a blood cell disorder--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, pale skin, feeling tired or short of breath, rapid heart rate, nosebleeds, bleeding gums;
    liver problems--nausea, upper stomach pain or swelling, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
    signs of metabolic acidosis--confusion, vomiting, lack of energy, irregular heartbeats;
    signs of a kidney stone--pain in your side or lower back, blood in your urine, painful or difficult urination; or
    severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
    Common side effects may include:

    nausea, vomiting, loss of appetite, diarrhea;
    numbness or tingling, especially in your arms and legs;
    drowsiness, confusion;
    hearing problems, ringing in your ears;
    increased urination; or
    altered sense of taste.
  • The recommended dosage is 1 capsule (500 mg) two times a day. Usually 1 capsule is administered in the morning and 1 capsule in the evening. It may be necessary to adjust the dose, but it has usually been found that dosage in excess of 2 capsules (1 g) does not produce an increased effect. The dosage should be adjusted with careful individual attention both to symptomatology and intraocular tension. In all cases, continuous supervision by a physician is advisable. In those unusual instances where adequate control is not obtained by the twice-a-day administration of DIAMOX SEQUELS, the desired control may be established by means of DIAMOX (tablets or parenteral). Use tablets or parenteral in accordance with the more frequent dosage schedules recommended for these dosage forms, such as 250 mg every four hours, or an initial dose of 500 mg followed by 250 mg or 125 mg every four hours, depending on the case in question.