Chlorpropamide is an oral diabetes medicine that helps control blood sugar levels by helping your pancreas produce insulin.

Chlorpropamide is used together with diet and exercise to treat type 2 diabetes. Chlorpropamide is sometimes used in combination with other diabetes medicines.

Chlorpropamide should not be used by itself to treat type 1 diabetes.

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  • Diabinese
  • Rare
    Abdominal or stomach pain
    agitation
    black, tarry stools
    chills
    clay-colored stools
    coma
    confusion
    continuing diarrhea
    continuing stomach pain
    convulsions
    dark urine
    decreased urine output
    depression
    diarrhea
    dizziness
    fast or irregular heartbeat
    fever
    headache
    hostility
    increased thirst
    irritability
    itching
    lethargy
    loss of appetite
    muscle pain or cramps
    muscle twitching
    nausea or vomiting
    rapid weight gain
    rash
    seizures
    shortness of breath
    stupor
    swelling of the face, ankles, or hands
    unpleasant breath odor
    unusual tiredness or weakness
    vomiting of blood
    yellow eyes or skin
    Incidence not known
    Anxiety
    back, leg, or stomach pains
    bleeding gums
    blood in the urine or stools
    blurred vision
    chest pain
    cold sweats
    cool, pale skin
    cough or hoarseness
    depression
    difficulty with breathing
    fever with or without chills
    fluid-filled skin blisters
    general body swelling
    general feeling of tiredness or weakness
    headache
    high fever
    increased hunger
    lower back or side pain
    nervousness
    nightmares
    nosebleeds
    painful or difficult urination
    pinpoint red spots on the skin
    sensitivity to the sun
    shakiness
    skin thinness
    slurred speech
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    swollen or painful glands
    tightness in the chest
    unusual bleeding or bruising
    wheezing
    Severity: Minor
    Some of the side effects that can occur with chlorpropamide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Indigestion
    passing of gas
    Less common
    Hives or welts
    redness of the skin
    weight loss
    Rare
    Blistering, peeling, or loosening of the skin
    cracks in the skin
    loss of heat from the body
    red, irritated eyes
    red, swollen skin
    scaly skin
    Incidence not known
    Increased sensitivity of the skin to sunlight
    redness or other discoloration of the skin
    severe sunburn
  • (chlorpropamide) Tablets, USP