Oxycodone is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Oxycodone acts on the central nervous system (CNS) to relieve pain.

Oxycodone extended-release tablets should not be used if you need pain medicine for just a short time, such as when recovering from surgery. Do not use this medicine to relieve mild pain, or in situations when non-narcotic medication is effective. This medicine should not be used to treat pain that you only have once in a while or “as needed”.

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  • Dazidox, Eth-Oxydose, Oxaydo, OxyCONTIN
  • Less common
    cold sweats
    difficult or labored breathing
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    tightness in the chest
    Abdominal or stomach pain
    bloating or swelling of the face, arms, hands, lower legs, or feet
    blood in the urine
    burning while urinating burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    decrease in the frequency of urination
    decrease in urine volume
    decreased urine output
    difficult or painful urination
    difficulty in passing urine (dribbling)
    difficulty with swallowing
    dry mouth
    fast, irregular, pounding, or racing heartbeat or pulse
    feeling of warmth or heat
    flushing or redness of the skin, especially on the face and neck
    frequent urination
    hives, itching, or skin rash
    increase in heart rate
    increased thirst
    increased volume of pale, dilute urine
    muscle pain or cramps
    nausea or vomiting
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    rapid breathing
    rapid weight gain
    severe constipation
    severe vomiting
    shakiness in the legs, arms, hands, or feet
    sunken eyes
    swelling or puffiness of the face
    swollen, painful, or tender lymph glands in the neck, armpit, or groin
    tingling of the hands or feet
    trembling or shaking of the hands or feet
    unusual tiredness or weakness
    unusual weight gain or loss
    wrinkled skin
    Incidence not known
    Blurred vision
    clay-colored stools
    cold, clammy skin
    dark urine
    fast, weak pulse
    irregular, fast, slow, or shallow breathing
    loss of appetite
    pale or blue lips, fingernails, or skin
    unpleasant breath odor
    very slow heartbeat
    yellow eyes or skin
    Get emergency help immediately if any of the following symptoms of overdose occur:

    Symptoms of overdose
    Change in consciousness
    chest pain or discomfort
    constricted, pinpoint, or small pupils (black part of the eye)
    decreased awareness or responsiveness
    extreme drowsiness
    loss of consciousness
    no muscle tone or movement
    severe sleepiness
    slow or irregular heartbeat
  • Usual Adult Dose for Pain The following dosing recommendations can only be considered suggested approaches to what is actually a series of clinical decisions over time in the management of the pain of each individual patient. -Oxycodone oral solution is available in 2 concentrations (5 mg/mL and 20 mg/mL); to avoid dosing errors, include total dose in mg and mL when prescribing and dispensing. Initial dose in opioid-naive patients: -Immediate Release: 5 to 15 mg orally every 4 to 6 hours -Oral solution 5 mg/mL: 5 to 15 mg orally every 4 to 6 hours -Titrate according to patient's pain response and tolerability