Daptomycin is an antibiotic that fights bacteria in the body.

Daptomycin is used to treat bacterial infections of the skin and underlying tissues.

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  • Cubicin
  • More common
    Bloating or swelling of the face, arms, hands, lower legs, or feet
    fever
    rapid weight gain
    tingling of the hands or feet
    unusual weight gain or loss
    Less common
    Abdominal or stomach pain
    agitation
    black, tarry stools
    bladder pain
    bloody or cloudy urine
    blurred vision
    chest pain or discomfort
    chills
    coma
    confusion
    convulsions
    cough
    decreased frequency or amount of urine
    decreased urine output
    depression
    diarrhea
    difficult or labored breathing
    difficult, burning, or painful urination
    dilated neck veins
    dizziness
    dry mouth
    extreme fatigue
    fainting
    faintness or lightheadedness when getting up suddenly from a lying or sitting position
    fast heartbeat
    frequent urge to urinate
    headache
    hostility
    increased blood pressure
    increased thirst
    irregular breathing
    irregular heartbeat
    irritability
    itching in the genital or other skin areas
    itching, pain, redness, swelling, tenderness, or warmth on the skin
    lethargy
    lightheadedness
    loss of appetite
    lower back or side pain
    mood changes
    muscle pain or cramps
    muscle twitching
    nausea
    nervousness
    numbness or tingling in the hands, feet, or lips
    pale skin
    pounding in the ears
    rapid weight gain
    rapid, shallow breathing
    scaling
    seizures
    shortness of breath
    slow or fast heartbeat
    sneezing
    sore throat
    stupor
    sweating
    swelling of the face, fingers, ankles, or hands
    tightness in the chest
    troubled breathing with exertion
    unusual bleeding or bruising
    usual tiredness or weakness
    vomiting of blood or material that looks like coffee grounds
    weight gain
    wheezing
    Rare
    Bleeding gums
    blood in the urine or stools
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    clay-colored stools
    dark urine
    difficulty with moving
    drowsiness
    eye pain
    feeling of warmth
    feeling unusually cold
    general feeling of illness
    headache
    hives
    hoarseness
    increase in bone pain
    irritation
    itching
    joint pain, stiffness, or swelling
    loss of appetite
    mood or mental changes
    muscle aching or cramping
    muscle spasms (tetany) or twitching
    no blood pressure or pulse
    pain in the joints
    pinpoint red spots on the skin
    rapid or irregular heartbeat
    rash
    redness of the face, neck, arms, and occasionally, upper chest
    redness of the skin
    redness, blistering, peeling, or loosening of the skin
    shivering
    skin rash, encrusted, scaly and oozing
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    stopping of heart
    swelling of the eyelids, face, lips, hands, or feet
    swollen glands
    swollen joints
    swollen, painful, or tender lymph glands in the neck, armpit, or groin
    trembling
    troubled breathing or swallowing
    twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
    unconsciousness
    unpleasant breath odor
    unusual bleeding or bruising
    vomiting of blood
    yellow eyes or skin
    Incidence not known
    Abdominal or stomach cramps
    abdominal or stomach tenderness
    diarrhea, watery and severe, which may also be bloody
    difficulty with swallowing
    dry cough
    pain
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    unusual weight loss
    Some of the side effects that can occur with daptomycin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
    diarrhea, mild
    difficulty having a bowel movement (stool)
    Less common
    Anxiety
    back pain
    blurred vision
    cold sweats
    coma
    cool, pale skin
    decreased appetite
    depression
    flushed, dry skin
    fruit-like breath odor
    increased hunger
    increased urination
    itching of the vagina or outside genitals
    lack or loss of strength
    limb pain
    nervousness
    nightmares
    pain during sexual intercourse
    shakiness
    skin rash
    sleeplessness
    slurred speech
    sweating
    thick, white, curd-like vaginal discharge without odor or with mild odor
    trouble sleeping
    unable to sleep
    unexplained weight loss
    Rare
    Acid or sour stomach
    bad, unusual, or unpleasant (after) taste
    belching
    change in taste
    continuing ringing or buzzing or other unexplained noise in the ears
    excess air or gas in the stomach or intestines
    feeling of constant movement of self or surroundings
    full feeling
    hearing loss
    heartburn
    indigestion
    pain or discomfort in the chest, upper stomach, or throat
    passing gas
    pressure in the stomach
    red, sore eyes
    seeing, hearing, or feeling things that are not there
    sensation of spinning
    sore mouth or tongue
    swelling of the abdominal or stomach area
    swelling or inflammation of the mouth
    weakness
    white patches in the mouth or on the tongue
  • (intravenous powder for injection)
  • Bacterial Infection

    Treating certain bacterial infections. It may be used in combination with other medicines to treat acne or certain amoeba infections. It may be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months. It may also be used to prevent or slow the progression of anthrax after exposure. Doryx delayed-release capsules are a tetracycline antibiotic. It works by slowing the growth of bacteria. Slowing the bacteria's growth allows the body's immune system to destroy the bacteria.