Dactinomycin is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Dactinomycin is used to treat different types of cancers that affect the kidneys, uterus, testicles, bones, muscles, joints, and soft tissues. Dactinomycin is also used to treat solid tumors.

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  • Cosmegen
  • More common
    Black, tarry stools
    blood in the urine or stools
    cough or hoarseness accompanied by fever or chills
    diarrhea (continuing)
    difficulty with swallowing
    fever or chills
    lower back or side pain accompanied by fever or chills
    painful or difficult urination accompanied by fever or chills
    pinpoint red spots on the skin
    sores in the mouth and on the lips
    stomach pain (continuing)
    unusual bleeding or bruising
    unusual tiredness or weakness
    Joint pain
    pain at the injection site
    swelling of the feet or lower legs
    yellow eyes or skin
    Incidence not known
    Abdominal or stomach cramps
    body aches or pain
    chapped, red, or swollen lips
    difficulty with breathing
    difficulty with moving
    difficulty with swallowing
    dryness or soreness of the throat
    flushing or redness of the skin
    growth retardation
    irregular heartbeats
    muscle aching or cramping
    muscle cramps in the hands, arms, feet, legs, or face
    muscle pains or stiffness
    numbness and tingling around the mouth, fingertips, or feet
    runny nose
    scaling, redness, burning, pain, or other signs of inflammation of the lips
    shortness of breath
    swollen joints
    tender, swollen glands in the neck
    unusually warm skin
    voice changes
    Some of the side effects that can occur with dactinomycin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Darkening of the skin
    general feeling of discomfort or weakness
    nausea and vomiting
    skin rash or acne
    unusual feeling of dullness or sluggishness
  • (intravenous powder for injection)