Cyclosporine lowers your body’s immune system. The immune system helps your body fight infections. The immune system can also fight or “reject” a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.

Cyclosporine is used to prevent organ rejection after a kidney, heart, or liver transplant. Cyclosporine is also used to treat severe psoriasis or severe rheumatoid arthritis.

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  • Gengraf, Neoral, SandIMMUNE
  • More common
    Abdominal or stomach pain or tenderness
    back pain
    black, tarry stools
    blurred vision
    chest pain
    chills
    clay colored stools
    cloudy urine
    cough
    dark urine
    decrease in urine output or decrease in urine-concentrating ability
    decreased appetite
    dizziness
    drowsiness
    fever
    headache
    headache, severe and throbbing
    itching
    loss of appetite
    muscle spasms (tetany) or twitching
    nausea and vomiting
    nervousness
    painful or difficult urination
    pounding in the ears
    shakiness in the legs, arms, hands, or feet
    shortness of breath
    skin rash
    slow or fast heartbeat
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    swelling of the feet or lower legs
    swollen glands
    trembling or shaking of the hands or feet
    unusual bleeding or bruising
    unusual tiredness or weakness
    yellow eyes or skin
    Less common
    Bleeding gums
    blood in the urine
    blood in the vomit
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    convulsions
    difficulty swallowing
    hives
    pale skin
    pinpoint red spots on the skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    severe or continuing stomach pain
    tightness in the chest
    troubled breathing with exertion
    Rare
    Bloating
    chest discomfort
    constipation
    darkened urine
    hoarseness
    indigestion
    lower back or side pain
    night sweats
    pain or discomfort in the arms, jaw, back, or neck
    pains in the stomach, side, or abdomen, possibly radiating to the back
    sweating
    vomiting of blood or material that looks like coffee grounds
    Severity: Minor
    Some of the side effects that can occur with cyclosporine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Abdominal or stomach discomfort
    bleeding, tender, or enlarged gums
    blemishes on the skin
    increased hair growth, especially on the face
    pain or tenderness around the eyes and cheekbones
    pimples
    stuffy or runny nose
    Less common
    Brittle fingernails
    burning feeling in the chest or stomach
    burning, dry, or itching eyes
    continuing ringing or buzzing or other unexplained noise in the ears
    cramps
    discharge or excessive tearing
    feeling of warmth
    hearing loss
    redness of the face, neck, arms, and occasionally, upper chest
    redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
    swelling of the breasts or breast soreness in both females and males
    weight loss
    Rare
    Blurred or loss of vision
    discouragement
    disturbed color perception
    double vision
    fear
    feeling sad or empty
    halos around lights
    irritability
    joint pain
    loss of interest or pleasure
    night blindness
    overbright appearance of lights
    tiredness
    trouble concentrating
    trouble sleeping
    tunnel vision
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    weakness
    weight loss
  • (oral capsule, oral liquid, injectable solution, oral solution, compounding powder)