Cyclophosphamide is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Cyclophosphamide is used to treat several types of cancer. Cyclophosphamide is also used to treat certain cases of nephrotic syndrome (kidney disease) in children.

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  • Cytoxan, Neosar, Cytoxan Lyophilized
  • More common
    Cough or hoarseness
    fever or chills
    lower back or side pain
    missing menstrual periods
    painful or difficult urination
    With high doses and/or long-term treatment
    Blood in the urine
    dizziness, confusion, or agitation
    fast heartbeat
    joint pain
    shortness of breath
    swelling of the feet or lower legs
    unusual tiredness or weakness
    Less common
    Black, tarry stools
    pinpoint red spots on the skin
    unusual bleeding or bruising
    Rare
    Frequent urination
    redness, swelling, or pain at the injection site
    sores in the mouth and on the lips
    sudden shortness of breath
    unusual thirst
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with cyclophosphamide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Darkening of the skin and fingernails
    loss of appetite
    nausea or vomiting
    Less common
    Diarrhea
    flushing or redness of the face
    headache
    increased sweating
    skin rash, hives, or itching
    stomach pain
    swollen lips
  • (intravenous powder for injection, oral tablet, oral capsule)