Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

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  • Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril
  • Rare
    Changes in the skin color of the face
    fast or irregular breathing
    large swellings that look like hives on the face, eyelids, mouth, lips, and/or tongue
    puffiness or swelling of the eyelids or the area around the eyes
    shortness of breath, troubled breathing, tightness in chest, and/or wheezing
    skin rash, hives, or itching
    Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking cyclobenzaprine:

    Symptoms of overdose
    Convulsions (seizures)
    drowsiness (severe)
    dry, hot, flushed skin
    fast or irregular heartbeat
    hallucinations (seeing, hearing, or feeling things that are not there)
    increase or decrease in body temperature
    troubled breathing
    unexplained muscle stiffness
    unusual nervousness or restlessness (severe)
    vomiting (occurring together with other symptoms of overdose)
    Severity: Moderate
    If any of the following side effects occur while taking cyclobenzaprine, check with your doctor or nurse as soon as possible:

    Clumsiness or unsteadiness
    mental depression or other mood or mental changes
    problems in urinating
    ringing or buzzing in the ears
    skin rash, hives, or itching occurring without other symptoms of an allergic reaction listed above
    unusual thoughts or dreams
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with cyclobenzaprine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Blurred vision
    dizziness or lightheadedness
    dryness of mouth
    Less common or rare
    Bloated feeling or gas, indigestion, nausea or vomiting, or stomach cramps or pain
    excitement or nervousness
    frequent urination
    general feeling of discomfort or illness
    muscle twitching
    numbness, tingling, pain, or weakness in hands or feet
    pounding heartbeat
    problems in speaking
    trouble in sleeping
    unpleasant taste or other taste changes
    unusual muscle weakness
    unusual tiredness
  • (oral tablet, oral capsule, extended release, compounding powder, oral and topical kit)