Esterified estrogens are female sex hormones necessary for many processes in the body.

Methyltestosterone is a man-made form of testosterone, a naturally occurring sex hormone that is produced in a man’s testicles. Small amounts of testosterone are also produced in a woman’s ovaries and adrenal system.

The combination of esterified estrogens and methyltestosterone is used to treat symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation.

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  • Covaryx, Covaryx HS, EEMT, EEMT DS, EEMT HS, Essian, Essian H.S., Estratest, Estratest H.S.
  • Call your doctor at once if you have a serious side effect such as:

    chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
    sudden numbness or weakness, especially on one side of the body;
    sudden severe headache, confusion, problems with vision, speech, or balance;
    swelling, rapid weight gain;
    confusion, unusual thoughts or behavior;
    pain, swelling, or tenderness in your stomach;
    nausea, stomach pain, loss of appetite jaundice (yellowing of the skin or eyes);
    breast lump, nipple discharge;
    acne, skin color changes, increased facial hair, male pattern baldness, voice changes; or
    changes in your menstrual periods, break-through bleeding.
    Less serious side effects may include:

    mild nausea, stomach upset;
    swollen or painful breasts;
    hair loss;
    depression, anxiety; or
    decreased sex drive, impotence, or difficulty having an orgasm.
  • Usual Dosage Range 1 capsule-shaped tablet of COVARYX® (1.25 mg/2.5 mg) or 1 to 2 capsule shaped tablets of COVARYX® H.S. (0.625 mg/1.25 mg) daily as recommended by the physician. Treated patients with an intact uterus should be monitored closely for signs of endometrial cancer and appropriate diagnostic measures should be taken to rule out malignancy in the event of persistent or recurring abnormal vaginal bleeding.