Coagulation factor IX is a man-made protein similar to a natural protein in the body that helps the blood to clot.

Coagulation factor IX is used to treat or prevent bleeding in people with hemophilia B. This medication is not for treating people with hemophilia A factor VIII deficiency.

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  • AlphaNine SD, Alprolix, BeneFIX, Mononine, Rixubis, BeneFIX 250 Int'l Units
  • Incidence not known
    blurred vision
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    difficult or labored breathing
    difficulty with swallowing
    dizziness or lightheadedness
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fast heartbeat
    hives, itching, or skin rash
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    pains in the chest, groin, or legs, especially calves of the legs
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    severe headaches of sudden onset
    sudden loss of coordination
    sudden onset of shortness of breath for no apparent reason
    sudden onset of slurred speech
    sudden shortness of breath or troubled breathing
    sudden vision changes
    tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over affected area
    tightness in the chest
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    unusual tiredness or weakness
    Severity: Minor
    Some of the side effects that can occur with coagulation factor ix may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Less common
    Change in taste
    loss of taste
    pain in the arms or legs
  • (intravenous powder for injection)