Clonidine brings down circulatory strain by diminishing the levels of specific chemicals in your blood. This permits your veins to unwind and your heart to pulsate all the more gradually and effortlessly.
Chlorthalidone is a thiazide diuretic (water pill) that keeps your body from retaining an excessive amount of salt, which can bring about liquid maintenance.
The blend of clonidine and chlorthalidone treats liquid maintenance (edema) in individuals with congestive heart disappointment, cirrhosis of the liver, or kidney issue, or edema brought about by taking steroids or estrogen. This prescription is likewise used to treat (hypertension).
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
dry mouth, increased thirst, drowsiness, restless feeling, nausea, vomiting, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting, or seizure (convulsions);
easy bruising or bleeding, unusual weakness;
red or purple spots on your skin;
urinating more or less than usual, or not at all;
feeling short of breath, even with mild exertion;
swelling, rapid weight gain;
numbness or tingly feeling; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
dry mouth, loss of appetite;
diarrhea, constipation, upset stomach;
feeling restless or nervous;
sleep problems (insomnia);
nightmares or unusual dreams;
breast swelling or tenderness;
mild itching or skin rash; or
impotence or loss of interest in sex.
Chlorthalidone is usually initiated at a dose of 25 mg once daily and may be increased to 50 mg if the response is insufficient after a suitable trial. Clonidine hydrochloride is usually initiated at a dose of 0.1 mg twice daily. Elderly patients may benefit from a lower initial dose. Further increments of 0.1 mg/day may be made if necessary until the desired response is achieved. The therapeutic doses most commonly employed have ranged from 0.2 to 0.6 mg per day in divided doses. One CLORPRES® (clonidine hydrochloride/chlorthalidone) Tablet administered once or twice daily can be used to administer a minimum of 0.1 mg clonidine hydrochloride and 15 mg chlorthalidone to a maximum of 0.6 mg clonidine hydrochloride and 30 mg chlorthalidone.