Clindamycin is an antibiotic. It fights bacteria in the body.

Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Clindamycin and tretinoin is a combination medicine used to treat severe nodular acne in adults and children who are at least 12 years old.

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  • Veltin, Ziana
  • More common
    Dryness and peeling of the skin
    flushing or redness of the skin
    unusually warm skin
    Less common
    Burning or stinging at the site of application
    changes in the color of the skin
    stomach cramps, tenderness, or pain
    watery or bloody diarrhea
    Severity: Minor
    Some of the side effects that can occur with clindamycin / tretinoin topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Less common
    dry skin
    muscle aches
    pain and tenderness around the eyes and cheekbones
    shortness of breath or troubled breathing
    sore throat
    stuffy or runny nose
    tightness of the chest or wheezing
    unusual tiredness or weakness
  • (topical gel)
  • Acne

    Minocycline is a tetracycline antibiotic that fights bacteria in the body. Minocycline is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Minocycline may also be used for purposes not listed in this medication guide.