Cilostazol is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). Cilostazol dilates arteries that supply blood to your legs. Cilostazol also improves circulation by keeping platelets in the blood from sticking together and clotting.

Cilostazol is used to treat the symptoms of intermittent claudication. This condition causes reduced blood flow to the legs, leading to pain while walking. Cilostazol improves your ability to walk longer distances without pain.

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  • Pletal
  • More common
    Fast or irregular heartbeat
    Less common
    Abnormal bleeding
    bloody or black tarry stools
    bruises or red spots on the skin
    nausea, heartburn, or indigestion (severe or continuing)
    stiff neck
    stomach pain, cramping, or burning (severe)
    swelling of the tongue
    vomiting of blood or material that looks like coffee grounds
    Incidence not known
    Abdominal or stomach pain
    area rash
    bleeding gums
    bleeding tendency
    blistering, peeling, loosening of the skin
    blood in the urine or stools
    blurred vision
    chest pain
    clay-colored stools
    cough or hoarseness
    coughing up blood
    dark urine
    difficulty with breathing
    fever with or without chills
    general feeling of tiredness or weakness
    headache, sudden and severe
    inability to speak
    itching of the eyes
    itching of the skin
    joint or muscle pain
    light-colored stools
    loss of appetite
    loss of consciousness
    lower back or side pain
    nausea and vomiting
    painful or difficult urination
    pinpoint red spots on the skin
    red skin lesions, often with a purple center
    red, irritated eyes
    skin rash
    slurred speech
    sores, ulcers, or white spots on the lips or in the mouth
    stomach pain
    swollen glands
    temporary blindness
    unpleasant breath odor
    unusual bleeding or bruising
    unusual tiredness or weakness
    weakness in the arm or leg on one side of the body, sudden and severe
    weakness of part of the body
    yellow eyes or skin
    If any of the following symptoms of overdose occur while taking cilostazol, get emergency help immediately:

    Symptoms of overdose
    dizziness or lightheadedness when getting up from a lying or sitting position
    fast or irregular heartbeat
    headache (severe)
    Severity: Minor
    Some of the side effects that can occur with cilostazol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Back pain
    increased cough
    pain or stiffness in the muscles
    pounding heartbeat
    runny or stuffy nose
    sore throat
    swelling of the arms or legs
    Less common
    Bone pain
    burning feeling in the throat or chest
    difficulty with swallowing
    pain or stiffness in the joints
    ringing or buzzing in the ears
    swelling of the face, fingers, or lower legs
    Incidence not known
    hot flushes
  • (oral tablet)