Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Chlorthalidone treats fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking steroids or estrogen. Chlorthalidone is also used to treat high blood pressure (hypertension).

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  • Thalitone, Hygroton
  • Incidence not known
    Abdominal or stomach pain
    black, tarry stools
    bleeding gums
    blistering, peeling, or loosening of skin
    bloating
    blood in urine or stools
    blurred vision
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    chills
    clay-colored stools
    cold sweats
    confusion
    constipation
    cough or hoarseness
    coughing up blood
    darkened urine
    diarrhea
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
    dry mouth
    fast heartbeat
    fatigue
    fever
    flushed, dry skin
    fruit-like breath odor
    general feeling of tiredness or weakness
    headache
    increased hunger
    increased thirst
    increased urination
    indigestion
    itching
    joint pain, stiffness, or swelling
    loss of appetite
    lower back or side pain
    nausea
    pain in joints or muscles
    painful or difficult urination
    pains in stomach, side, or abdomen, possibly radiating to the back
    pinpoint red spots on skin
    red irritated eyes
    red skin lesions, often with a purple center
    redness, soreness or itching skin
    shortness of breath
    skin rash
    sore throat
    sores, ulcers, or white spots on lips or in mouth
    sores, welting, or blisters
    sugar in the urine
    sweating
    swelling of feet or lower legs
    swollen glands
    tightness in chest
    troubled breathing
    unpleasant breath odor
    unusual bleeding or bruising
    unusual tiredness or weakness
    unusual weight loss
    vomiting
    vomiting of blood
    weight loss
    wheezing
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with chlorthalidone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Incidence not known
    Cramping
    decreased interest in sexual intercourse
    difficulty having a bowel movement (stool)
    feeling of constant movement of self or surroundings
    hives
    inability to have or keep an erection
    increased sensitivity of skin to sunlight
    loss in sexual ability, desire, drive, or performance
    muscle spasm
    redness or other discoloration of skin
    restlessness
    sensation of spinning
    severe sunburn
    weakness
  • (oral tablet)