Cerezyme (imiglucerase) may be a semisynthetic sort of Associate in Nursing catalyst that happens naturallywithin the body. it’s used as Associate in Nursing catalyst replacement in individuals with kind I Gaucher illness.
Gaucher illness may be a genetic condition during which the body lacks the catalyst required to interrupt down surefatty materials (lipids). Lipids will build up within the body, inflicting symptoms like simple bruising or harm, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that ar simply broken.

Cerezyme might improve the condition of the liver, spleen, bones, and blood cells in individuals with kind I Gaucherillness. However, this medication isn’t a cure for this condition.

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  • Cerezyme
  • Get emergency medical help if you have any of these signs of an allergic reaction to Cerezyme: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    Some side effects may occur during or shortly after the injection. Tell your caregiver right away if you feel dizzy, itchy, light-headed, sweaty, or have chest pain, cough, trouble breathing, or flushing (warmth, redness, or tingly feeling).

    Call your doctor at once if you have:

    fever, chills, cough with yellow or green mucus;
    stabbing chest pain, wheezing, feeling short of breath; or
    worsening or no improvement in your Gaucher disease symptoms.
    Common Cerezyme side effects may include:

    stomach pain, nausea, vomiting, diarrhea;
    fast heartbeats;
    headache, dizziness;
    back pain;
    fever, chills, tired feeling;
    mild rash; or
    itching, burning, swelling, or other discomfort around the IV needle.
  • Usual Adult Dose for Gaucher Disease: Initial dosage: ranges from 2.5 units/kg of body weight 3 times a week to 60 units/kg once every 2 weeks. Imiglucerase for injection is administered by intravenous infusion over 1 to 2 hours. Dosage should be individualized to each patient. Disease severity may dictate that treatment be initiated at a relatively high dose or relatively frequent administration. Usual Pediatric Dose for Gaucher Disease: Greater than or equal to 2 years of age: Initial dosage: ranges from 2.5 units/kg of body weight 3 times a week to 60 units/kg once every 2 weeks. Imiglucerase for injection is administered by intravenous infusion over 1 to 2 hours. Dosage should be individualized to each patient. Disease severity may dictate that treatment be initiated at a relatively high dose or relatively frequent administration.