Restoring function to central venous access devices that have become clogged with clotted blood. It may also be used for other conditions as determined by your doctor.

Cathflo Activase is a tissue plasminogen activator (tPA). It works by helping to break down unwanted blood clots.

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  • Cathflo Activase
  • More common
    Bleeding from puncture sites and wounds
    bleeding gums
    coughing up blood
    difficulty with breathing or swallowing
    dizziness
    headache
    increased menstrual flow or vaginal bleeding
    nosebleeds
    paralysis
    prolonged bleeding from cuts
    red or black, tarry stools
    red or dark brown urine
    shortness of breath
    Rare
    Chills
    confusion
    fainting
    fast heartbeat
    fever
    lightheadedness
    pain in chest, groin, or legs, especially the calves
    pain, redness, or swelling in arm or leg
    rapid, shallow breathing
    severe, sudden headache
    slurred speech
    sudden loss of coordination
    sudden, severe weakness or numbness in arm or leg
    sudden, unexplained shortness of breath
    vision changes
    Incidence not determined
    Anxiety
    blue lips and fingernails
    blue or pale skin
    blurred vision
    chest pain or discomfort
    chest pain, possibly moving to the left arm, neck, or shoulder
    convulsions
    cool, sweaty skin
    cough
    coughing that sometimes produces a pink frothy sputum
    decreased urine output
    dilated neck veins
    extreme fatigue
    hives or welts
    hoarseness
    increased sweating
    itching
    large, hive-like swelling on mouth, lips, or tongue
    loss of bladder control
    low blood pressure or pulse
    muscle spasm or jerking of all extremities
    nausea or vomiting
    pain or discomfort in arms, jaw, back, or neck
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    redness of skin
    skin rash
    slow or irregular breathing or heartbeat
    sudden loss of consciousness
    sweating
    swelling of face, fingers, feet, lower legs, or ankles
    tightness in chest
    troubled breathing
    unconsciousness
    unusual tiredness or weakness
    weight gain
    wheezing
  • (alteplase) injection, powder, lyophilized, for solution