Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Captopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. Captopril lowers blood pressure and also relieves symptoms of fluid retention.

Hydrochlorothiazide and captopril is a combination medicine used to treat hypertension (high blood pressure).

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  • Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25
  • More common
    Black, tarry stools
    chest pain
    chills
    cough
    fever
    painful or difficult urination
    shortness of breath
    sore throat
    sores, ulcers, or white spots on lips or in mouth
    swollen glands
    unusual bleeding or bruising
    unusual tiredness or weakness
    Less common
    Blurred vision
    cloudy urine
    confusion
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
    fast, pounding, or irregular heartbeat or pulse
    sweating
    Rare
    Arm, back or jaw pain or discomfort
    bloody urine
    chest discomfort
    chest tightness or heaviness
    decreased blood pressure
    decreased frequency or amount of urine
    dilated neck veins
    increased need to urinate
    increased thirst
    irregular breathing
    large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    loss of appetite
    lower back or side pain
    nausea
    paleness or cold feeling in fingertips and toes
    passing urine more often
    problems in urination or increase in amount of urine
    swelling of face, fingers, feet or lower legs
    tingling or pain in fingers or toes when exposed to cold
    troubled breathing
    vomiting
    weight gain
    wheezing
    Severity: Minor
    Some of the side effects that can occur with captopril / hydrochlorothiazide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Difficulty in moving
    itching skin
    muscle pain or stiffness
    pain in joints
    rash
    Less common
    Change in taste
    loss of taste
  • (oral tablet)