Capecitabine is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body.

Capecitabine is used to treat colon cancer, and breast or colorectal cancer that has spread to other parts of the body.

Capecitabine is often used in combination with other cancer medications and/or radiation treatments.

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  • Xeloda
  • More common
    Abdominal or stomach pain
    diarrhea
    nausea
    numbness, pain, tingling, or other unusual sensations in the palms of the hands or bottoms of the feet
    pain, blistering, peeling, redness, or swelling of the palms of the hands or bottoms of the feet
    pain, redness, swelling, sores, or ulcers in your mouth or on your lips
    unusual tiredness or weakness
    vomiting
    Less common or rare
    Abdominal or stomach cramping or pain (severe)
    agitation
    back pain
    bleeding and bruising
    bleeding gums
    blood in the urine or stools
    bloody nose
    bloody or black, tarry stools
    blurred vision
    burning, dry, or itching eyes
    chest pain
    chills
    clumsiness or unsteadiness
    cold
    collapse
    coma
    confusion
    constipation
    convulsions
    cough or hoarseness (accompanied by fever or chills)
    cough producing mucus
    coughing or spitting up blood
    dark urine
    decreased frequency or amount of urine
    difficulty with breathing
    difficulty with swallowing or pain in the back of throat or chest when swallowing
    discharge from the eyes
    drowsiness
    dry mouth
    excessive tearing
    extra heartbeats
    eye redness, irritation, or pain
    fainting
    fast or irregular heartbeat
    fever or chills
    flu-like symptoms
    hallucinations
    headache, sudden and severe
    heavier menstrual periods
    high fever
    hot, red skin on the feet or legs
    inability to speak
    increased menstrual flow or vaginal bleeding
    increased thirst
    irritability
    itching in the genital or other skin areas
    lightheadedness
    light-colored stools
    loss of consciousness
    lower back or side pain (accompanied by fever or chills)
    muscle aches or cramps
    muscle spasms
    nosebleeds
    numbness or tingling in the hands, feet, or lips
    painful or difficult urination (accompanied by fever or chills)
    painful, swollen feet or legs
    pain, tenderness, or swelling in the upper abdominal or stomach area
    pale skin
    paralysis
    pinpoint red spots on the skin
    problems with coordination
    prolonged bleeding from cuts
    rapid, shallow breathing
    red or dark brown urine
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
    scaling
    seizures
    severe constipation
    skin rash or itching
    slow or irregular heartbeat
    slurred speech
    sneezing, sore throat, or stuffy nose
    sores, ulcers, or white spots on the lips or in the mouth
    stiff neck
    stomach bloating, burning, or cramping
    swelling of the face, fingers, feet, or lower legs
    swelling of the lymph nodes
    swollen glands
    temporary blindness
    tiredness or weakness
    trouble with speaking
    troubled breathing or tightness in the chest
    unexplained nosebleeds
    unusual bleeding or bruising
    unusual lump or swelling in the chest
    vomiting blood or material that looks like coffee grounds
    weakness in the arm or leg on one side of the body, sudden and severe
    weight gain or loss
    white patches in the mouth or throat or on the tongue
    white patches with diaper rash
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with capecitabine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Less common
    Burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
    changes or discoloration in the fingernails or toenails
    difficulty with moving
    discouragement
    dizziness
    headache
    heartburn
    increased sensitivity of the skin to sunlight
    muscle pain
    pain
    pain and redness of the skin at the place of x-ray treatment
    pain in the joints or limbs
    red, sore eyes
    sunken eyes
    thirst
    trouble sleeping
    weakness
    wrinkled skin
    Rare
    Bone pain
    change in color of treated skin
    difficulty with walking
    discouragement
    feeling of constant movement of self or surroundings
    feeling sad or empty
    full or bloated feeling or pressure in the stomach
    general feeling of discomfort or illness
    hot flushes
    impaired balance
    increased sweating
    joint pain
    lack of appetite
    loss of interest or pleasure
    muscle weakness
    noisy breathing
    pain in the rectum
    pain, swelling, or redness in the joints
    passing less gas
    rough, scratchy sound to voice
    runny nose
    sensation of spinning
    shakiness in the legs, arms, hands, or feet
    shivering
    sores on the skin
    swelling of abdominal or stomach area
    tremor or shaking of the hands or feet
    trouble concentrating
    voice changes
  • (oral tablet)