Preventing and treating certain kinds of headaches (eg, migraines, migraine variants, “histaminic cephalalgia”). It may also be used for other conditions as determined by your doctor.
Caffeine/ergotamine is a combination of 2 vasoconstrictors. It works by constricting blood vessels in the lining of the brain, which helps to decrease the pain from migraine headaches.
Seek medical attention right away if any of these SEVERE side effects occur while taking caffeine / ergotamine:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue color of the fingers or toes; chest pain or tightness; cold or pale fingers or toes; diarrhea; dizziness; hallucinations; headache; irregular heartbeat; leg cramps or weakness; mental or mood changes; muscle pain; numbness or tingling of the hands, feet, or skin; ringing in the ears; seizure; severe or persistent nausea or vomiting; shortness of breath; swelling; temporary fast or slow heartbeat; vomiting; weak pulse.
(oral tablet, rectal suppository)