Preventing and treating certain kinds of headaches (eg, migraines, migraine variants, “histaminic cephalalgia”). It may also be used for other conditions as determined by your doctor.

Caffeine/ergotamine is a combination of 2 vasoconstrictors. It works by constricting blood vessels in the lining of the brain, which helps to decrease the pain from migraine headaches.

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  • Cafergot
  • Nausea.

    Seek medical attention right away if any of these SEVERE side effects occur while taking caffeine / ergotamine:
    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blue color of the fingers or toes; chest pain or tightness; cold or pale fingers or toes; diarrhea; dizziness; hallucinations; headache; irregular heartbeat; leg cramps or weakness; mental or mood changes; muscle pain; numbness or tingling of the hands, feet, or skin; ringing in the ears; seizure; severe or persistent nausea or vomiting; shortness of breath; swelling; temporary fast or slow heartbeat; vomiting; weak pulse.
  • (oral tablet, rectal suppository)