Treating opioid dependence. It should be used as part of a complete treatment plan. It may also be used for other conditions as determined by your doctor.

Buprenorphine/naloxone is an opioid (narcotic) partial agonist-antagonist. It works in the brain and nervous system to help prevent withdrawal symptoms in someone who has stopped taking narcotics.

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  • Suboxone and Zubsolv
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking buprenorphine / naloxone:

    More common
    Cough or hoarseness
    feeling faint, dizzy, or lightheaded
    feeling of warmth or heat
    fever or chills
    flushing or redness of the skin, especially on the face and neck
    headache
    lower back or side pain
    painful or difficult urination
    sweating
    Incidence not known
    Bloating or swelling of the face, arms, hands, lower legs, or feet
    rapid weight gain
    tingling of the hands or feet
    unusual weight gain or loss
    If any of the following symptoms of overdose occur while taking buprenorphine / naloxone, get emergency help immediately:

    Symptoms of overdose
    Blurred vision
    confusion
    difficult or troubled breathing
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    drowsiness
    irregular, fast, slow, or shallow breathing
    pale or blue lips, fingernails, or skin
    pinpoint pupils
    relaxed and calm feeling
    sleepiness
    unusual tiredness or weakness
    Severity: Minor
    Some of the side effects that can occur with buprenorphine / naloxone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Abdominal or stomach pain
    difficulty having a bowel movement (stool)
    lack or loss of strength
    nausea
    pain
    trouble sleeping
    vomiting
    Less common
    Back pain
    diarrhea
    runny nose
    sneezing
    stuffy nose
  • (sublingual tablet, sublingual film, buccal film)