Blinatumomab is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Blinatumomab is used to treat a type of blood cancer called Philadelphia chromosome-negative B-precursor acute lymphoblastic leukemia (ALL). This medicine is given after other cancer treatments have been tried without success.

Blinatumomab was approved by the US Food and Drug Administration (FDA) on an “accelerated” basis. In clinical studies, blinatumomab produced complete remission in many people. However, further studies are needed to determine if this medicine can lengthen survival time.

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  • Blincyto
  • More common:
    bloating or swelling of the face, arms, hands, lower legs, or feet
    blurred vision
    chest pain
    cough or hoarseness
    fever or chills
    lower back or side pain
    painful or difficult urination
    pale skin
    pinpoint red spots on the skin
    sore throat
    stiff neck
    tightness in the chest
    tingling of the hands or feet
    troubled breathing
    unusual bleeding or bruising
    unusual tiredness or weakness
    unusual weight gain or loss
    Incidence not known:
    Cloudy urine
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    lack or loss of strength
    persistent bleeding or oozing from puncture sites, mouth, or nose
    stomach pain
    swelling of the hands, ankles, feet, or lower legs
    ulcers, sores, or white spots in the mouth
    Severity: Minor
    Some of the side effects that can occur with blinatumomab may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Bone, joint, or muscle pain
    change in urination
    decreased appetite
    difficulty having a bowel movement (stool)
    dry mouth
    increased hunger or thirst
    irregular heartbeat
    muscle pain or cramps
    pain in the arms or legs
    shakiness in the legs, arms, hands, or feet
  • (intravenous powder for injection)