Immune globulin injection is used to prevent or treat diseases that occur when your body has a weak immune system. Immune globulin contains antibodies that make your immune system stronger. It is used for patients who have primary humoral immunodeficiency (PI), idiopathic thrombocytopenic purpura (ITP), chronic immune thrombocytopenic purpura, or chronic inflammatory demyelinating polyneuropathy (CIDP). It is also used to improve muscle strength and disability in patients with multifocal motor neuropathy (MMN). Immune globulin injection belongs to a group of medicines known as immunizing agents.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not included in product labeling, immune globulin is used in certain patients with the following medical conditions:

Chronic parvovirus B19 infection (treatment).
Dermatomyositis (treatment).
Guillain-Barré syndrome (treatment).
Hyperimmunoglobulinemia E syndrome (treatment).
Infections in low birth weight preterm high-risk neonates (prevention and treatment).
Lambert-Eaton myasthenic syndrome (treatment).
Relapsing-remitting multiple sclerosis (treatment).

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  • More common:
    Chills
    cough
    fast, pounding, or irregular heartbeat or pulse
    fever
    noisy breathing
    tightness in the chest
    troubled breathing
    unusual tiredness or weakness
    Less common:
    Bluish coloring of the lips or nail beds
    burning sensation in the head
    faintness or lightheadedness
    Rare:
    Difficulty with swallowing
    hives or welts
    itching, especially of the feet or hands
    reddening of the skin, especially around the ears
    swelling of the eyes, face, or inside of the nose
    Incidence not known:
    Back, leg, or stomach pains
    blistering, peeling, or loosening of the skin
    change in vision
    changes in urination
    chest pain or discomfort
    cold, clammy, or pale skin
    confusion
    convulsions
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fever
    headache that is severe and occurs suddenly
    light-colored stools
    loss of consciousness
    low blood pressure or pulse
    muscle spasm or jerking of all extremities
    nausea or vomiting
    pains in the chest, groin, or legs, especially calves of the legs
    shakiness in the legs, arms, hands, or feet
    skin blisters
    slow breathing
    slurred speech that occurs suddenly
    sores, ulcers, or white spots in the mouth or on the lips
    sudden, severe weakness or numbness in the arm or leg
    sweating
    swelling in the legs and ankles
    tightness in the chest
    unusual bleeding or bruising
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with immune globulin intravenous may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Diarrhea
    dizziness
    headache
    joint pain
    muscle pain
    redness, swelling, itching, or pain at the injection site
    skin rash
    Less common:
    Hip pain
    leg cramps
    Incidence not known:
    Feeling of warmth
    redness of the face, neck, arms, and occasionally, upper chest
    stomach pain
    swollen glands
    tiredness
    weakness
  • (intravenous solution, intravenous powder for injection)