Sotalol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).

Sotalol is used to help keep the heart beating normally in people with certain heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart). Sotalol is used in people with ventricular tachycardia or ventricular fibrillation.

Another form of this medicine, called sotalol AF, is used to treat heart rhythm disorders of the atrium (the upper chambers of the heart that allow blood to flow into the heart). Sotalol AF is used in people with atrial fibrillation or atrial flutter.

Sotalol (Betapace, Sorine, Sotylize) is not used for the same conditions that sotalol AF (Betapace AF) is used for.

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  • Betapace, Sorine, Sotylize
  • More common
    Blurred vision
    chest pain or discomfort
    difficult or labored breathing
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fast, slow, irregular, pounding, or racing heartbeat or pulse
    lightheadedness, dizziness, or fainting
    nausea and vomiting
    swelling of the face, fingers, feet, or lower legs
    tightness in the chest
    unusual tiredness or weakness
    Less common
    Abdominal or stomach pain or swelling
    body aches or pain
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    cough or hoarseness
    decreased alertness
    difficulty with speaking
    dilated neck veins
    double vision
    extreme fatigue
    feeling of warmth or heat
    fever or chills
    flushing or redness of the skin, especially on the face and neck
    inability to move the arms, legs, or facial muscles
    inability to speak
    irregular breathing
    joint pain or swelling
    loss of voice
    lower back or side pain
    noisy breathing
    painful, burning, or difficult urination
    pounding in the ears
    slow speech
    weight gain
    Fast breathing
    pinpoint red spots on the skin
    If any of the following symptoms of overdose occur while taking sotalol, get emergency help immediately:

    Symptoms of overdose
    cold sweats
    cool, pale skin
    increased hunger
    slurred speech
    Severity: Minor
    Some of the side effects that can occur with sotalol may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Acid or sour stomach
    difficulty with sleeping
    heartburn or indigestion
    pain in the arms or legs
    Less common
    Changes in vision
    decreased sexual performance or desire
    loss of appetite
    mood changes
    night blindness
    passing gas
    skin rash
    weight changes
    Feeling of constant movement of self or surroundings
    hair loss or thinning of the hair
    itching skin
    muscle aching or cramping
    muscle pains or stiffness
    quick to react or overreact emotionally
    sensation of spinning
    severe sunburn
  • (sotalol hydrochloride) tablet