Rho(D) immune globulin is used to treat immune thrombocytopenic purpura (ITP) in patients with Rh-positive blood. ITP is a type of blood disorder where the person has a very low number of platelets. Platelets help to clot the blood. Rho(D) immune globulin is also used to prevent antibodies from forming after a person with Rh-negative blood receives a transfusion with Rh-positive blood, or during pregnancy when a mother has Rh-negative blood and the baby is Rh-positive. It belongs to a group of medicines called immunizing agents. Rho(D) immune globulin works to boost the immune system and prevent excessive bleeding.

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  • BayRho-D
  • Bloody urine
    decreased frequency of urination or amount of urine
    fever
    increased blood pressure
    increased thirst
    loss of appetite
    lower back pain
    nausea or vomiting
    pale skin
    swelling of the face, fingers, or lower legs
    troubled breathing
    unusual bleeding or bruising
    unusual tiredness or weakness
    weight gain
  • Usual Adult Dose for Idiopathic (Immune) Thrombocytopenic Purpura Rhophylac(R): 250 international units (50 mcg) per kg, IV, at 2 mL per 15 to 60 seconds WinRho(R): -Initial dose: 250 international units (50 mcg) per kg, IV, over 3 to 5 minutes; may be divided into 2 doses on separate days if desired. -Maintenance dose: 125 to 300 international units/kg (25 to 60 mcg/kg), IV, over 3 to 5 minutes Use: Immune thrombocytopenic purpura (ITP): -Raising platelet counts in Rho (D)-positive, non-splenectomized chronic ITP Usual Adult Dose for Rh-Isoimmunization Dose and route varies for each product. Rh-incompatible pregnancy: RhoGAM(R): 1500 international units (300 mcg), IM, at gestational week 26 to 28, or within 72 hours of birth of an RHo (D) positive baby. Rhophylac(R): 1500 international units (300 mcg), IV or IM, at gestational week 29 to 30; repeat dose within 72 hours of birth of an RHo (D) positive baby. WinRho(R): 1500 international units (300 mcg), IV or IM, at gestational week 28; give an additional 600 international units (120 mcg) dose within 72 hours of birth of an RHo (D) positive baby.