Norethindrone is a form of progesterone, a female hormone. Norethindrone prevents ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Norethindrone is used for birth control (contraception) to prevent pregnancy. Norethindrone is also used to treat menstrual disorders, endometriosis, or abnormal vaginal bleeding caused by a hormone imbalance.

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  • Aygestin, Camila, Errin, Jolivette, Nor-QD, Nora-Be, Ortho Micronor
  • Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Stop using this medication and call your doctor at once if you have any of these serious side effects:

    sudden numbness or weakness, especially on one side of the body;
    sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance;
    pain or swelling in one or both legs;
    migraine headache;
    swelling in your hands or feet, rapid weight gain;
    symptoms of depression (sleep problems, weakness, mood changes);
    severe pelvic pain;
    chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling; or
    nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
    Less serious side effects may include:

    mild nausea, vomiting, bloating, stomach cramps;
    breast pain, swelling, or tenderness;
    freckles or darkening of facial skin;
    increased acne or hair growth;
    changes in weight;
    vaginal itching or discharge;
    skin itching or rash;
    changes in your menstrual periods, decreased sex drive; or
    mild headache.
  • 2.5 to 10 mg AYGESTIN may be given daily for 5 to 10 days to produce secretory transformation of an endometrium that has been adequately primed with either endogenous or exogenous estrogen. Progestin withdrawal bleeding usually occurs within three to seven days after discontinuing AYGESTIN therapy. Patients with a past history of recurrent episodes of abnormal uterine bleeding may benefit from planned menstrual cycling with AYGESTIN. Endometriosis Initial daily dosage of 5 mg AYGESTIN for two weeks. Dosage should be increased by 2.5 mg per day every two weeks until 15 mg per day of AYGESTIN is reached. Therapy may be held at this level for six to nine months or until annoying breakthrough bleeding demands temporary termination.