Aspirin is in a group of drugs called salicylates (sa-LIS-il-ates). It works by reducing substances in the body that cause pain, fever, and inflammation.

Dipyridamole keeps platelets in your blood from sticking together to form clots.

Aspirin and dipyridamole is a combination medicine used to reduce the risk of stroke in people who have had blood clots or a “mini-stroke” (also called a transient ischemic attack or TIA).

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  • Aggrenox
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking aspirin / dipyridamole:

    More common:
    Abdominal or stomach pain
    vomiting
    Less common:
    Bleeding from the rectum
    bloody mucous or unexplained nosebleeds
    bloody or black, tarry stools
    confusion
    convulsions (seizures)
    difficulty with breathing
    difficulty with speaking
    double vision
    inability to move the arms, legs, or facial muscles
    inability to speak
    memory loss
    pale skin
    purple or red spots on skin
    slow speech
    tightness in the chest
    troubled breathing (exertional)
    unusual bleeding or bruising
    vomiting of blood or material that looks like coffee grounds
    Rare:
    Abdominal or stomach fullness
    blood in the urine
    chills
    clay-colored stools
    collection of blood under the skin
    cough
    deep, dark purple bruise
    gaseous abdominal or stomach pain
    itching, pain, redness, or swelling of the eye or eyelid
    loss of appetite
    nausea
    noisy breathing
    recurrent fever
    skin rash or hives (severe)
    watering of the eyes
    yellow eyes or skin
    If any of the following symptoms of overdose occur while taking aspirin / dipyridamole, get emergency help immediately:

    Symptoms of overdose:
    Blurred vision
    continuing ringing or buzzing or other unexplained noise in the ears
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fast or irregular heartbeat
    flushes
    hearing loss
    restlessness
    sweating
    unusual tiredness or weakness
    warm feeling
    Severity: Minor
    Some of the side effects that can occur with aspirin / dipyridamole may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Acid or sour stomach
    belching
    diarrhea
    difficulty with moving
    headache
    heartburn
    indigestion
    muscle pain or stiffness
    pain, swelling, or redness in the joints
    stomach discomfort or upset
    Less common or rare:
    Back pain
    burning feeling in the chest or stomach
    loss of strength or energy
    rectal pain or swelling
    sleepiness or unusual drowsiness
    taste loss
    tenderness in the stomach area
  • (oral capsule, extended release)