Arzerra (ofatumumab) could be a antibody that affects the actions of the body’s system. organism antibodies arcreated to focus on and destroy solely bound cells within the body. this might facilitate to safeguard healthy cells from injury.
Arzerra is employed to treat chronic leucaemia. In some patients, ofatumumab is given with another medicationknown as alkalating agent.
Arzerra is usually given once different medications are tried while not success.
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Get emergency medical help if you have signs of an allergic reaction to Arzerra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, confused, itchy, tingly, or have chest pain, jaw or arm pain, back pain, stomach pain, wheezing, chest tightness, or trouble breathing. These reactions can occur during the injection or within 24 hours afterward.
Call your doctor right away if you have signs of a serious brain infection: change in your mental state, decreased vision, weakness on one side of your body, or problems with speech or walking. These symptoms may start gradually and get worse quickly.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Call your doctor at once if you have:
fever, chills, cough with yellow or green mucus;
stabbing chest pain, wheezing, feeling short of breath;
liver problems--nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
low blood cell counts--fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed; or
signs of tumor cell breakdown--lower back pain, blood in your urine, little or no urination; numbness or tingly feeling around your mouth; muscle weakness or tightness; fast or slow heart rate, weak pulse, feeling short of breath; confusion, fainting.
Common Arzerra side effects may include:
fever, cough, flu symptoms;
cold symptoms such as stuffy nose, sneezing, sore throat;
mild rash; or
Arzerra is injected into a vein through an IV. A healthcare provider will give you this injection. Ofatumumab must be given slowly through an IV infusion, and one dose can take up to several hours to complete. Arzerra is usually given in a treatment cycle over several weeks, beginning with one infusion per week. Then you will receive your infusions less often, depending on the type of CLL for which you are being treated. Your dosing schedule may change with further doses. Your doctor will determine how long to treat you with Arzerra. You will be given other IV or oral (by mouth) medications to prevent certain side effects of Arzerra. You may need to start using these medications up to 2 hours before the start of your ofatumumab infusion. You may also need to take antiviral medications if you are found to have any risk factors for hepatitis B. Follow your doctor's dosing instructions very carefully. Arzerra can cause hepatitis B to come back or get worse. You will need frequent blood tests to check your liver function.