Chloroquine is a medication to treat or prevent malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites in the red blood cells of the human body.

Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

Chloroquine is used to treat and to prevent malaria. Chloroquine is also used to treat infections caused by amoebae.

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  • Aralen Phosphate
  • Black, tarry stools
    bleeding gums
    blistering, peeling, or loosening of the skin
    blood in the urine or stools
    blurred vision
    chest pain
    difficulty with swallowing
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fast heartbeat
    joint or muscle pain
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    lower back or side pain
    painful or difficult urination
    pale skin
    pinpoint red spots on the skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    red skin lesions, often with a purple center
    red, irritated eyes
    skin rash, hives, or itching
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    swollen or painful glands
    tightness in the chest
    unusual bleeding or bruising
    unusual tiredness or weakness
    Incidence not known:
    Blurred vision or any other change in vision
    change in near or distance vision
    continuing ringing or buzzing or other unexplained noise in the ears
    dark urine
    difficulty in focusing the eyes
    difficulty with speaking
    disturbed color perception
    double vision
    general tiredness and weakness
    halos around lights
    hearing loss
    inability to move the eyes
    increased blinking or spasms of the eyelid
    light-colored stools
    loss of balance control
    muscle trembling, jerking, or stiffness
    muscular pain, tenderness, wasting, or weakness
    nausea and vomiting
    night blindness
    overbright appearance of lights
    shuffling walk
    sticking out of the tongue
    stiffness of the limbs
    trouble breathing
    tunnel vision
    twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
    uncontrolled movements, especially of the face, neck, and back
    upper right abdominal or stomach pain
    yellow eyes and skin
  • Suppression — Adult Dose: 500 mg (= 300 mg base) on exactly the same day of each week. Pediatric Dose: The weekly suppressive dosage is 5 mg calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight. If circumstances permit, suppressive therapy should begin two weeks prior to exposure. However, failing this in adults, an initial double (loading) dose of 1 g (= 600 mg base), or in children 10 mg base/kg may be taken in two divided doses, six hours apart. The suppressive therapy should be continued for eight weeks after leaving the endemic area. For Treatment of Acute Attack Adults: An initial dose of 1 g (= 600 mg base) followed by an additional 500 mg (= 300 mg base) after six to eight hours and a single dose of 500 mg (= 300 mg base) on each of two consecutive days. This represents a total dose of 2.5 g chloroquine phosphate or 1.5 g base in three days. The dosage for adults of low body weight and for infants and children should be determined as follows: First dose: 10 mg base per kg (but not exceeding a single dose of 600 mg base). Second dose: (6 hours after first dose) 5 mg base per kg (but not exceeding a single dose of 300 mg base). Third dose: (24 hours after first dose) 5 mg base per kg. Fourth dose: (36 hours after first dose) 5 mg base per kg.