Treating depression. It is also used to prevent autumn-winter seasonal depression in patients with seasonal affective disorder (SAD). It may also be used for other conditions as determined by your doctor.

Aplenzin extended-release tablets are an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

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  • Aplenzin
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking bupropion:

    More common:
    Anxiety
    dry mouth
    hyperventilation
    irregular heartbeats
    irritability
    restlessness
    shaking
    shortness of breath
    trouble sleeping
    Less common:
    Buzzing or ringing in the ears
    headache (severe)
    skin rash, hives, or itching
    Rare:
    Confusion
    fainting
    false beliefs that cannot be changed by facts
    having extreme distrust of people
    seeing, hearing, or feeling things that are not there
    seizures (convulsions)
    trouble concentrating
    Incidence not known:
    Actions that are out of control
    anger
    assaulting others
    attacking others
    being aggressive
    being impulsive
    chest pain or discomfort
    fast or pounding heartbeat
    force
    inability to sit still
    need to keep moving
    sweating
    talking, feeling, or acting with excitement
    Severity: Minor
    Some of the side effects that can occur with bupropion may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Abdominal or stomach pain
    constipation
    decrease in appetite
    dizziness
    increased sweating
    trembling
    weight loss (unusual)
    Less common:
    Blurred vision
    change in sense of taste
    drowsiness
    frequent need to urinate
    sore throat
    unusual feeling of wellbeing
  • (bupropion hydrobromide) tablet, extended release