Acetaminophen and codeine oral suspension is used to relieve mild to moderate pain. The oral tablets are used to relieve mild to moderately severe pain.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including serious liver damage. Although rare, use of acetaminophen has been reported to lead to liver transplantation and death, usually at high doses and when multiple acetaminophen-containing products have been used.

Codeine belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.

When codeine is used for a long time, it may become habit-forming, causing mental or physical dependence when it is used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

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  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking acetaminophen / codeine:

    More common:
    Difficult or troubled breathing
    irregular, fast or slow, or shallow breathing
    pale or blue lips, fingernails, or skin
    shortness of breath
    Incidence not known:
    Black, tarry stools
    bleeding gums
    blood in the urine or stools
    cough or hoarseness
    difficulty with swallowing
    fast heartbeat
    fever with or without chills
    general feeling of tiredness or weakness
    lower back or side pain
    painful or difficult urination
    pinpoint red spots on the skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    skin rash
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    tightness in the chest
    unusual bleeding or bruising
    unusual tiredness or weakness
    If any of the following symptoms of overdose occur while taking acetaminophen / codeine, get emergency help immediately:

    Symptoms of overdose:
    Abdominal or stomach pain
    bloody or cloudy urine
    constricted, pinpoint, or small pupils (black part of the eye)
    dark urine
    increased sweating
    light-colored stools
    loss of appetite
    loss of consciousness
    sudden decrease in amount of urine
    unpleasant breath odor
    vomiting of blood
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with acetaminophen / codeine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    relaxed and calm
    Incidence not known:
    Difficulty having a bowel movement (stool)
    false or unusual sense of well-being
  • (oral capsule, oral liquid, oral tablet, oral suspension)