Anakinra reduces the actions of chemicals in the body that are involved in inflammatory and immune responses.

Anakinra is used to treat the symptoms of moderate to severe rheumatoid arthritis in adults. Anakinra may also help slow the progress of the disease.

Anakinra is usually given after other arthritis medications have been tried without successful treatment of symptoms.

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  • Kineret
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking anakinra:

    More common:
    fever or chills
    itching, pain, redness, swelling, tenderness or warmth on the skin
    joint pain
    muscle aches and pains
    nausea or vomiting
    runny nose or sneezing
    sore throat
    Less common or rare:
    Difficulty with swallowing
    hives, itching, or rash
    swelling of the face or lips
    unusual bruising or bleeding
    unusual tiredness or weakness
    Incidence not known:
    fast heartbeat
    hives or welts
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
    Severity: Minor
    Some of the side effects that can occur with anakinra may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Abdominal or stomach pain
    bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
    difficulty with moving
    muscle aches or stiffness
  • (subcutaneous solution)