Anagrelide lowers platelets (blood-clotting cells) in the body, which helps prevent blood clots from forming.

Anagrelide is used to treat a blood cell disorder called thrombocythemia (also called thrombocytosis), which occurs when your body produces too many platelet cells.

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  • Agrylin
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking anagrelide:

    More common:
    Bloating or swelling of the face, arms, hands, lower legs, or feet
    body aches or pain
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    congestion
    cough
    difficult or labored breathing
    dryness or soreness of the throat
    fast, irregular, pounding, or racing heartbeat or pulse
    fever
    hoarseness
    rapid weight gain
    runny nose
    tender, swollen glands in the neck
    tightness in the chest
    trouble with swallowing
    voice changes
    Less common:
    Anxiety
    blurred vision
    burning while urinating
    chills
    cold sweats
    confusion
    decreased urine output
    dehydration
    difficult or painful urination
    dilated neck veins
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    extreme fatigue
    general feeling of discomfort or illness
    headache
    irregular breathing
    joint pain
    large, flat, blue, or purplish patches in the skin
    loss of appetite
    muscle aches and pains
    nausea or vomiting
    noisy breathing
    pale skin
    redness of the face, neck, arms, and occasionally, upper chest
    severe pain or pressure in the chest or the jaw, neck, back, or arms
    sudden severe headache or weakness
    swollen, painful, or tender lymph glands in the neck, armpit, or groin
    trouble sleeping
    troubled breathing with exertion
    unusual bleeding or bruising
    unusual tiredness or weakness
    vomiting of blood or material that looks like coffee grounds
    weight gain
    Incidence not known:
    Abdominal or stomach pain or tenderness
    clay colored stools
    dark urine
    decreased appetite
    dry cough
    general feeling of tiredness or weakness
    rapid breathing
    skin rash or itching
    yellow eyes or skin
    Severity: Minor
    Some of the side effects that can occur with anagrelide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Acid or sour stomach
    back pain
    belching
    diarrhea
    excess air or gas in the stomach or intestines
    full feeling
    general feeling of discomfort or illness
    heartburn
    hives or welts
    indigestion
    lack or loss of strength
    pain
    passing gas
    stomach discomfort, upset, or pain
    Less common:
    Burning feeling in the chest or stomach
    change in vision
    confusion
    constipation
    continuing ringing or buzzing or other unexplained noise in the ears
    depression
    difficulty with moving
    double vision
    hair loss or thinning of the hair
    hearing loss
    impaired vision
    increased sensitivity of the skin to sunlight
    leg cramps
    loss of memory
    muscle pain or stiffness
    problems with memory
    redness or other discoloration of the skin
    seeing double
    severe sunburn
    sleepiness or unusual drowsiness
    stuffy nose
    swelling or inflammation of the mouth
    swollen joints
  • (oral capsule)