Amlodipine is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.

Valsartan is an angiotensin II receptor antagonist. Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Amlodipine and valsartan is a combination medicine used to treat high blood pressure (hypertension). This medicine is usually given after others have been tried without successful treatment of hypertension.

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  • Exforge
  • More common:
    Bloating or swelling of the face, arms, hands, lower legs, or feet
    rapid weight gain
    tingling of the hands or feet
    unusual weight gain or loss
    Less common:
    Body aches or pain
    chills
    cough
    difficulty with breathing
    dizziness
    ear congestion
    fever
    headache
    loss of voice
    muscle aches
    sneezing
    sore throat
    stuffy or runny nose
    unusual tiredness or weakness
    Rare:
    Ankle, knee, or great toe joint pain
    bloody or cloudy urine
    blurred or loss of vision
    burning feeling in the chest or stomach
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    cold sweats
    confusion
    congestion
    cough producing mucus
    diarrhea
    difficult, burning, or painful urination
    disturbed color perception
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
    dry mouth
    fast, irregular, pounding, or racing heartbeat or pulse
    flushed, dry skin
    heart murmur
    hives
    hoarseness
    indigestion
    itching
    joint pain, stiffness, or swelling
    loss of appetite
    nausea
    pain in the lower back, bottom, or hips
    pain in the upper leg
    pain or tenderness around the eyes and cheekbones
    rash
    redness of the skin
    stomach cramps, tenderness, or pain
    sweating
    swelling of the eyelids, face, lips, hands, or feet
    tightness of the chest
    trouble with swallowing
    troubled breathing
    vomiting
    watery or bloody diarrhea
    weakness
    If any of the following symptoms of overdose occur while taking amlodipine / valsartan, get emergency help immediately:

    Symptoms of overdose:
    Chest discomfort
    cold, clammy skin
    fast, weak pulse
    flushing
    lightheadedness or fainting
    slow heartbeat
    Severity: Minor
    Some of the side effects that can occur with amlodipine / valsartan may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Rare:
    Acid or sour stomach
    back pain
    belching
    bone pain
    continuing ringing or buzzing or other unexplained noise in the ears
    difficulty having a bowel movement (stool)
    difficulty with moving
    fear or nervousness
    feeling sad or empty
    full or bloated feeling
    hearing loss
    heartburn
    inability to have or keep an erection
    increased sensitivity to sunlight
    irritability
    itching, pain, redness, or swelling of the eye or eyelid
    lack or loss of strength
    loss in sexual ability, desire, drive, or performance
    loss of interest or pleasure
    muscle aching or cramping
    pain in the arms or legs
    passing gas
    pressure in the stomach
    redness in the joints
    redness of the skin
    sensation of spinning
    skin rash, encrusted, scaly, and oozing
    sleepiness or unusual drowsiness
    swelling of the abdominal or stomach area
    tiredness
    toothache
    trouble concentrating
    unable to sleep
    unusually warm skin
    watering of the eyes
  • (oral tablet)