Amikacin® (amikacin sulfate) is an amicoglycoside antibiotic derived from kanamycin. It is intended in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria to include but not limited to – Pseudomonas Species, Escherichia Coli, Proteus species, and other Klebsiella-Enetrobacter-Serratia species.
In the clinical aspect of the drug, It is to reduce the development of drug-resistant bacteria and maintain the viability of amikacin sulfate injection. Medical doctors strongly advise that Amikacin Sulfate should only be used to treat infections that are diagnostically proven to be bacterial in nature. As clinical research and trials show to be effective in staphylococcal infections and may be considered as initial therapy under given circumstances. In cases of neonatal sepsis, concomitant therapy with a penicillin type drug may be indicatively supplemented because of the possibility of infections due to gram-positive organisms such as pneumococci species.
Aminoglycosides can cause fetal harm when carried out to a pregnant woman. Aminoglycosides cross the placenta and there have been several reports of total irreversible, bilateral congenital deafness in children whose mothers received streptomycin during pregnancy. Serious side effects to the fetus or newborns have not been recorded in the treatment of pregnant women with other aminoglycosides, the potential for morbidity still exists. Clinical studies of amikacin have been performed in rats and mice and revealed no evidence of impaired fertility or harm to the fetus due to amikacin. There are no well-controlled studies in pregnant women, but investigational experience does not include any positive evidence of adverse effects to the fetus. If this drug is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be warned and informed of the potential hazard to the fetus.
Side effect includes but not limited to:
- Sudden hearing loss
- Weakness of the injection site
- Nausea and Vomiting
- Feeling of Tiredness
- Acute hearing loss
- loss of balance
*If symptoms persists, consult your physician immediately
Dosage varies and it is computed by weight of the individual. Consult your physician for more details