Treating panic disorder. It may also be used to treat other conditions as determined by your doctor.

Alprazolam extended-release tablets are a benzodiazepine. It works in the brain to decrease anxiety.

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  • Xanax XR
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking alprazolam:

    More common:
    Being forgetful
    changes in patterns and rhythms of speech
    clumsiness or unsteadiness
    difficulty with coordination
    feeling sad or empty
    lack of appetite
    loss of interest or pleasure
    relaxed and calm
    shakiness and unsteady walk
    sleepiness or unusual drowsiness
    slurred speech
    trouble concentrating
    trouble in speaking
    trouble performing routine tasks
    trouble sleeping
    unsteadiness, trembling, or other problems with muscle control or coordination
    unusual tiredness or weakness
    Less common:
    Abdominal or stomach pain
    blurred vision
    body aches or pain
    burning, crawling, itching, numbness, prickling, "pins and needles, or tingling feelings
    changes in behavior
    clay-colored stools
    confusion about identity, place, and time
    dark urine
    decrease in frequency of urination
    decrease in urine volume
    difficult or labored breathing
    difficulty in moving
    difficulty in passing urine (dribbling)
    difficulty with concentration
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
    dry mouth
    ear congestion
    environment seems unreal
    fear or nervousness
    feeling of unreality
    feeling warm
    general feeling of discomfort or illness
    inability to move eyes
    inability to sit still
    increased blinking or spasms of the eyelid
    irregular heartbeats
    joint pain
    lack or loss of self-control
    loss of bladder control
    loss of coordination
    loss of memory
    loss of voice
    mood or mental changes
    muscle aching or cramping
    muscle pain or stiffness
    muscle weakness
    nasal congestion
    need to keep moving
    painful urination
    problems with memory
    runny nose
    seeing, hearing, or feeling things that are not there
    sense of detachment from self or body
    shortness of breath
    sore throat
    sticking out of the tongue
    swollen joints
    tightness in the chest
    trouble in breathing, speaking, or swallowing
    trouble with balance
    twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
    uncontrolled twisting movements of the neck, trunk, arms, or legs
    unpleasant breath odor
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    unusual facial expressions
    unusually deep sleep
    unusually long duration of sleep
    vomiting of blood
    yellow eyes or skin
    Actions that are out of control
    attack, assault, or force
    chest pain
    continuing ringing or buzzing or other unexplained noise in ears
    decreased awareness or responsiveness
    deep or fast breathing with dizziness
    ear pain
    false or unusual sense of well-being
    fast, irregular, pounding, or racing heartbeat or pulse
    feeling jittery
    feeling unusually cold
    generalized slowing of mental and physical activity
    hearing loss
    lack of feeling or emotion
    loss of control of the legs
    loss of strength or energy
    numbness of the feet, hands, and around mouth
    severe sleepiness
    shakiness in the legs, arms, hands, or feet
    sleep talking
    talking, feeling, and acting with excitement
    thoughts of killing oneself
    unable to sleep
    unusual weak feeling
    voice changes
    Incidence not known:
    General tiredness and weakness
    light-colored stools
    stomach pain, continuing
    upper right abdominal pain
    Severity: Minor
    Some of the side effects that can occur with alprazolam may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Absent, missed, or irregular menstrual periods
    decreased appetite
    decreased interest in sexual intercourse
    decreased sexual performance or desire abnormal ejaculation
    difficulty having a bowel movement (stool)
    inability to have or keep an erection
    increased appetite
    increased in sexual ability, desire, drive, or performance
    increased interest in sexual intercourse
    increased weight
    loss in sexual ability, desire, drive, or performance
    stopping of menstrual bleeding
    watering of mouth
    weight loss
    Less common:
    Abdominal bloating and cramping
    blistering, crusting, irritation, itching, or reddening of the skin
    change in taste bad unusual or unpleasant (after) taste
    cracked, dry, or scaly skin
    double vision
    feeling of warmth
    heavy bleeding
    menstrual changes
    pelvic pain
    redness of the face, neck, arms, and occasionally, upper chest
    seeing double
    sudden sweating
    unexplained runny nose or sneezing
    Acid or sour stomach
    bigger, dilated, or enlarged pupils (black part of eye)
    change in color vision
    difficulty seeing at night
    feeling of constant movement of self or surroundings
    feeling of relaxation
    hives or welts
    increased sensitivity of eyes to sunlight
    redness of skin
    runny nose
    sensation of spinning
    stomach discomfort, upset, or pain
    stuffy nose
    Incidence not known:
    Blistering, peeling, or loosening of the skin
    red, irritated eyes
    red skin lesions, often with a purple center
    sores, ulcers, or white spots in the mouth or on the lips
    swelling of the breasts or breast soreness in both females and males
    unexpected or excess milk flow from breasts
  • (oral tablet, oral tablet, extended release, oral solution, oral concentrate, oral tablet, disintegrating, compounding powder)