Treating type 2 diabetes in certain patients. It is used along with diet and exercise.

Alogliptin/pioglitazone is a dipeptidyl peptidase-4 (DPP-4) inhibitor and thiazolidinedione combination. It works by increasing the amount of insulin released by your body and decreasing the amount of sugar made by your body. It also helps make your body more sensitive to the action of insulin.

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  • Oseni
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking alogliptin / pioglitazone:

    More common:
    Anxiety
    blurred vision
    chest pain
    chills
    cold sweats
    coma
    confusion
    cool, pale skin
    decreased urine output
    depression
    dilated neck veins
    dizziness
    extreme fatigue
    fast heartbeat
    headache
    increased hunger
    irregular breathing
    irregular heartbeat
    nausea
    nightmares
    seizures
    shakiness
    slurred speech
    swelling of the face, fingers, feet, or lower legs
    tightness in the chest
    troubled breathing
    unusual tiredness or weakness
    weight gain
    Rare:
    Blistering, peeling, or loosening of the skin
    bloating
    blood in the urine
    constipation
    cough
    darkened urine
    diarrhea
    difficulty with swallowing
    feeling of discomfort
    fever
    frequent, strong, or increased urge to urinate
    hives
    indigestion
    inflammation of the joints
    itching
    joint or muscle pain
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    loss of appetite
    muscle aches
    pain in the back, lower abdomen, or stomach
    painful urination
    pains in the stomach, side, or abdomen, possibly radiating to the back
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    rash
    red skin lesions, often with a purple center
    red, irritated eyes
    sore throat
    sores, ulcers, or white spots in the mouth or on the lips
    swollen lymph glands
    vomiting
    yellow eyes or skin
    Incidence not known:
    Change in vision
    general feeling of tiredness or weakness
    light-colored stools
    stomach pain, continuing
    Severity: Minor
    Some of the side effects that can occur with alogliptin / pioglitazone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Less common:
    Back pain
    body aches or pain
    ear congestion
    loss of voice
    sneezing
    stuffy or runny nose
  • (oral tablet)