Netupitant and palonosetron is a combination medicine used in adults to prevent nausea and vomiting caused by medicine to treat cancer (chemotherapy).

Netupitant and palonosetron helps prevent nausea and vomiting that occurs both during your chemotherapy treatment, or that occurs later on (delayed nausea and vomiting).

Netupitant and palonosetron is not for preventing nausea or vomiting caused by factors other than chemotherapy.

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  • Akynzeo
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking netupitant / palonosetron:

    Incidence not known:
    Agitation
    confusion
    dizziness
    fever
    hearing or seeing things that are not there
    muscle twitching
    overactive reflexes
    poor coordination
    shivering
    sweating
    trembling or shaking
    Severity: Minor
    Some of the side effects that can occur with netupitant / palonosetron may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Headache
    fatigue
    unusual tiredness or weakness
    Less common:
    constipation
    flushing or redness of the skin
    heartburn
    indigestion
    stomach discomfort, upset, or pain
  • (netupitant and palonosetron) capsule