Riociguat lowers blood pressure in your lungs, helping your heart pump blood more efficiently.

Riociguat is used to treat chronic thromboembolic pulmonary hypertension (CTEPH) in people who cannot be treated with surgery, or in people who have undergone surgery but still have symptoms. Riociguat can treat certain symptoms of CTEPH and can improve your ability to exercise.

Riociguat is used to treat pulmonary arterial hypertension (PAH). Riociguat can improve your ability to exercise and help prevent PAH from getting worse.

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  • Adempas
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking riociguat:

    More common:
    Confusion
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    nosebleeds
    unusual tiredness or weakness
    Less common:
    Abdominal or stomach pain or swelling
    bloating or swelling of the face, arms, hands, lower legs, or feet
    bloody or black, tarry stools
    bruising or purple areas on the skin
    coughing or spitting up blood
    decreased alertness
    fast, irregular, pounding, or racing heartbeat or pulse
    heavy non-menstrual vaginal bleeding
    rapid weight gain
    troubled breathing with exertion
    vomiting of blood or material that looks like coffee grounds
    Severity: Minor
    Some of the side effects that can occur with riociguat may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Diarrhea
    headache
    heartburn or indigestion
    nausea or vomiting
    stuffy nose
    Less common:
    Difficulty having a bowel movement (stool)
  • (oral tablet)