Riociguat lowers blood pressure in your lungs, helping your heart pump blood more efficiently.
Riociguat is used to treat chronic thromboembolic pulmonary hypertension (CTEPH) in people who cannot be treated with surgery, or in people who have undergone surgery but still have symptoms. Riociguat can treat certain symptoms of CTEPH and can improve your ability to exercise.
Riociguat is used to treat pulmonary arterial hypertension (PAH). Riociguat can improve your ability to exercise and help prevent PAH from getting worse.
You should check with your doctor immediately if any of these side effects occur when taking riociguat:
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
unusual tiredness or weakness
Abdominal or stomach pain or swelling
bloating or swelling of the face, arms, hands, lower legs, or feet
bloody or black, tarry stools
bruising or purple areas on the skin
coughing or spitting up blood
fast, irregular, pounding, or racing heartbeat or pulse
heavy non-menstrual vaginal bleeding
rapid weight gain
troubled breathing with exertion
vomiting of blood or material that looks like coffee grounds
Some of the side effects that can occur with riociguat may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
heartburn or indigestion
nausea or vomiting
Difficulty having a bowel movement (stool)