Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect, which allows excess oils and dirt to be easily washed away from the skin.

Adapalene is similar to vitamin A. It helps the skin renew itself.

Adapalene and benzoyl peroxide topical (for the skin) is a combination medicine used to treat acne in adults and children who are at least 9 years old.

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  • Epiduo, Epiduo Pump, Epiduo Forte
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking adapalene / benzoyl peroxide topical:

    More common:
    Dryness and peeling of the skin
    flushing or redness of the skin
    unusually warm skin
    Less common:
    Blistering, burning, crusting, or flaking of the skin
    burning, itching, redness, skin rash, swelling, or soreness at the application site
    scaling, severe redness, or swelling of the skin
    Incidence not known:
    Skin pain
    sunburn
    Severity: Minor
    Some of the side effects that can occur with adapalene / benzoyl peroxide topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Incidence not known:
    Burning, dry, or itching eyes
    change in the color of the treated skin
    discharge or excessive tearing
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
    skin rash, encrusted, scaly, and oozing
    swelling of the face
  • (topical gel)
  • Acne

    Minocycline is a tetracycline antibiotic that fights bacteria in the body. Minocycline is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Minocycline may also be used for purposes not listed in this medication guide.