Adalimumab reduces the effects of a substance in the body that can cause inflammation.

Adalimumab is used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and a chronic skin condition called hidradenitis suppurativa. It is also used to treat Crohn’s disease or ulcerative colitis, after other drugs have been tried without successful treatment of symptoms.

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  • Humira, Humira Pen, Humira Pen Crohns Disease/Ulcerative Colitis Starter Package, Humira Pen Psoriasis Starter Package, Humira Pediatric, Humira Pediatric Crohn's Disease Starter Pack
  • More common:
    Abdominal or stomach fullness
    body aches or pain
    cough or hoarseness
    ear congestion
    gas with abdominal or stomach pain
    lightheadedness
    loss of voice
    lower back or side pain
    muscle aches and pains
    nasal congestion
    pain or tenderness around the eyes or cheekbones
    rapid and sometimes shallow breathing
    shivering
    sunken eyes
    thirst
    trouble sleeping
    warmth on the skin
    wrinkled skin
    Less common:
    A sore on the skin of the breast that does not heal
    abdominal or stomach pain
    abnormal vaginal bleeding or discharge
    agitation
    arm, back, or jaw pain
    black, tarry stools
    bleeding from the gums or nose
    blindness
    bloating or swelling of the face, arms, hands, lower legs, or feet
    blood in the stool or change in bowel habits
    bloody or cloudy urine
    blurred vision
    broken bones
    change in size, shape, or color of an existing mole
    change in skin color
    chest pain
    chest tightness or heaviness
    chills
    clear or bloody discharge from the nipple
    cold hands and feet
    confusion
    constipation
    cough
    coughing or spitting up blood
    decreased urination
    decreased vision
    depression
    difficult or frequent urination
    difficulty with breathing
    difficulty, burning, or painful urination
    dimpling of the breast skin
    dizziness
    drowsiness
    eye pain
    fainting
    fast, slow, or irregular heartbeat
    fever
    forgetfulness
    frequent urge to urinate
    general feeling of illness
    hair loss
    hallucinations
    headache
    increased thirst
    inverted nipple
    irregular breathing
    irregular pulse
    irritability
    itching or rash
    light colored stools
    loss of appetite
    lump in the breast or under your arm
    lump or swelling in the abdomen or stomach
    mole that leaks fluid or bleeds
    muscle cramps or spasms
    nausea
    new mole
    night sweats
    no blood pressure or pulse
    noisy breathing
    numbness or tingling in your arms, legs, or face
    pain, redness, or swelling in the arms or legs without any injury present
    pale skin
    persistent non-healing sore on your skin
    pink growth
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    raised, firm, or bright red patch
    redness or swelling of the breast
    seizures
    sharp back pain just below your ribs
    shiny bump on your skin
    slurred speech or problems with swallowing
    sneezing
    sore throat
    sores, ulcers, or white spots on the lips or mouth
    spitting up blood
    stiff neck
    stopping of the heart
    sudden high fever or low grade fever for months
    sweating
    swelling of the face, fingers, feet, or lower legs
    swollen glands
    swollen neck veins
    tightness in the chest
    tiredness
    trouble breathing with activity
    trouble thinking
    unconsciousness
    unexplained bruising or bleeding
    unpleasant breath odor
    unusual tiredness or weakness
    unusual weight gain or loss
    visual disturbances
    vomiting
    vomiting of blood or material that looks like coffee grounds
    yellow skin or eyes
    Incidence not known:
    Blistering, peeling, or loosening of the skin
    diarrhea
    joint or muscle pain
    pinpoint red spots on the skin
    red skin lesions, often with a purple center
    red, irritated eyes
    red, scaling, or crusted skin
    unusual bleeding or bruising
    Severity: Minor
    Some of the side effects that can occur with adalimumab may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Bladder pain
    bleeding
    burning
    coldness
    discoloration of the skin
    feeling of pressure
    general feeling of discomfort or illness
    hives
    lumps
    numbness
    pounding in the ears
    redness
    scarring
    soreness
    stinging
    swelling
    tenderness
    tingling
    ulceration
    warmth
    Less common:
    Abnormal healing
    decrease in height
    difficulty with moving
    difficulty with swallowing
    difficulty with walking
    dry mouth
    heartburn
    indigestion
    loss of hearing
    loss of strength or energy
    menstrual changes
    muscle or joint stiffness, tightness, or rigidity
    muscle pain or weakness
    pain in the back, ribs, arms, or legs
    shakiness in the legs, arms, hands, and feet
    sores
    stomach pain, fullness, or discomfort
    swelling or redness in the joints
    weakness
  • (subcutaneous kit)