Corticotropin is a man-made form of a hormone that occurs naturally in the body.

Corticotropin is also used to treat many different conditions such as multiple sclerosis, psoriatic or rheumatoid arthritis, ankylosing spondylitis, lupus, severe allergic reactions, breathing disorders, and inflammatory conditions of the eyes. Corticotropin is also used to treat infantile spasms in children younger than 2 years old.

Corticotropin can reduce the symptoms of many disorders, but it is not a cure for these conditions. Corticotropin is also not expected to slow the progress of any disease.

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  • Acthar Gel, H.P.
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking corticotropin:

    More common:
    Backache
    blurred vision
    body aches or pain
    chest pain
    cough
    difficulty with breathing
    dizziness
    ear congestion
    earache
    facial hair growth in females
    fever or chills
    fractures
    full or round face, neck, or trunk
    headache
    increased thirst or urination
    irritability
    loss of sexual desire or ability
    loss of voice
    menstrual irregularities
    muscle wasting
    nasal congestion
    nervousness
    pounding in the ears
    redness or swelling in the ear
    runny nose
    shortness of breath
    slow or fast heartbeat
    sneezing
    sore throat
    tightness in the chest
    troubled breathing
    unusual tiredness or weakness
    wheezing
    white patches in the mouth or throat or on the tongue
    white patches with diaper rash
    Less common:
    Convulsions (seizures)
    Incidence not known:
    Accumulation of pus
    bruising
    bulging soft spot on the head of an infant
    change in the ability to see colors, especially blue or yellow
    cold, clammy skin
    confusion
    decreased range of motion
    decreased urine output
    dilated neck veins
    extreme fatigue
    eyeballs bulge out of eye sockets
    fast, weak pulse
    full or bloated feeling
    heartburn
    insomnia
    irregular breathing
    irregular heartbeat
    joint pain
    large, flat, blue, or purplish patches in the skin
    lightheadedness
    limp
    loss of appetite
    nausea and vomiting
    pressure in the stomach
    severe headache
    small red or purple spots on the skin
    sweating
    swelling of abdominal or stomach area
    swelling of the face, fingers, feet, or lower legs
    swollen, red, or tender area of infection
    trouble healing
    weight gain
    wheezing
    Incidence not known-For adults only
    Bloating
    chills
    confusion
    constipation
    coughing up blood
    darkened urine
    fast heartbeat
    fever
    headache
    headache, sudden and severe
    increased sweating
    indigestion
    loss of appetite
    pain in the muscles
    pains in the stomach, side, or abdomen, possibly radiating to the back
    redness of the face
    skin rash
    unusual weight loss
    weakness
    yellow eyes or skin
    Incidence not known-For infants only
    Decreased carbohydrate tolerance
    hypokalemic alkalosis
    reversible brain shrinkage
    Severity: Minor
    Some of the side effects that can occur with corticotropin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Blemishes on the skin
    diarrhea
    pimples
    Less common:
    Increased or decreased appetite
    Incidence not known:
    Increased hair growth, especially on the face
    menstrual changes
    muscle weakness
    Incidence not known-For adults only
    Feeling of constant movement of self or surroundings
    sensation of spinning
    thinning of the skin
  • (repository corticotropin) injection