Relieving headaches, migraine headaches, toothaches, muscle aches, premenstrual or menstrual aches, or other minor aches and pains (eg, due to sinusitis, arthritis, or colds). It may also be used for other conditions as determined by your doctor.

Acetaminophen/aspirin/caffeine is an analgesic and antipyretic combination. It works by blocking substances in the body that cause pain and inflammation.

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  • Excedrin and Vanquish
  • Heartburn; nausea; upset stomach.

    Seek medical attention right away if any of these SEVERE side effects occur while taking acetaminophen / aspirin / caffeine:
    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); confusion; fainting; hearing loss; ringing in the ears; symptoms of liver problems (eg, dark urine, pale stools, persistent loss of appetite, right-upper stomach pain, yellowing of the skin or eyes); unusual tiredness.
  • (oral tablet, oral powder for reconstitution)