Aripiprazole is used alone or together with other medicines to treat mental conditions such as bipolar I disorder (manic-depressive illness), major depressive disorder, and schizophrenia. It is also used in children to treat irritability associated with autistic disorder and Tourette syndrome. Aripiprazole works in the brain to change how certain chemicals affect patients. It is an antipsychotic agent.

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  • aripiprazole
  • Severity: Major
    You should check with your doctor immediately if any of these side effects occur when taking aripiprazole:

    More common:
    Difficulty with speaking
    drooling
    loss of balance control
    muscle trembling, jerking, or stiffness
    restlessness
    shuffling walk
    stiffness of the limbs
    twisting movements of the body
    uncontrolled movements, especially of the face, neck, and back
    Less common:
    Blurred vision
    dizziness
    headache
    inability to move the eyes
    increased blinking or spasms of the eyelid
    nervousness
    pounding in the ears
    slow or fast heartbeat
    sticking out the tongue
    trouble with breathing or swallowing
    unusual facial expressions
    Rare:
    Convulsions
    fast heartbeat
    high fever
    high or low blood pressure
    increased sweating
    lip smacking or puckering
    loss of bladder control
    muscle spasm or jerking of all extremities
    puffing of the cheeks
    rapid or worm-like movements of the tongue
    severe muscle stiffness
    sudden loss of consciousness
    tiredness
    uncontrolled chewing movements
    uncontrolled movements of the arms and legs
    unusually pale skin
    Incidence not known:
    Hives or welts, itching, or skin rash
    itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    redness of the skin
    tightness in the chest
    unusual tiredness or weakness
    If any of the following symptoms of overdose occur while taking aripiprazole, get emergency help immediately:

    Symptoms of overdose:
    Bigger, dilated, or enlarged pupils (black part of the eye)
    diarrhea
    fast, pounding, or irregular heartbeat or pulse
    increased sensitivity of the eyes to light
    lack or loss of strength
    nausea
    sleepiness or unusual drowsiness
    vomiting
    Severity: Minor
    Some of the side effects that can occur with aripiprazole may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common:
    Acid or sour stomach
    anxiety
    belching
    blurred vision
    difficulty having a bowel movement (stool)
    dry mouth
    fear
    fever
    headache
    heartburn
    hyperventilation
    inability to sit still
    indigestion
    irritability
    lightheadedness
    need to keep moving
    nervousness
    rash
    runny nose
    shaking
    sleeplessness
    sore throat
    stomach discomfort, upset, or pain
    trouble sleeping
    unable to sleep
    weight gain
    Less common:
    Accidental injury
    bloating or swelling of the face, arms, hands, lower legs, or feet
    body aches or pain
    congestion
    coughing
    difficulty with moving
    dryness or soreness of throat
    hoarseness
    increased appetite
    increased salivation
    joint pain
    muscle aching or cramping
    muscle pains or stiffness
    rapid weight gain
    sneezing
    stuffy nose
    swollen joints
    tender, swollen glands in the neck
    tingling of the hands or feet
    tremor
    unusual weight gain or loss
    voice changes
  • (oral tablet, oral tablet, disintegrating, oral solution, intramuscular solution, intramuscular powder for injection, extended release, intramuscular suspension, extended release)